Why the Brits are Smarter Than We Are!
Or Irrefutable evidence that all Athletes Need Dr Dave's Best Supplements!
Part 1
by Dave Woynarowski, M.D. (aka Dr. Dave)
It's embarrassing to admit it but our friends across the pond have it all over us in a least one department, athletic supplementation.
Several articles came across my desk lately that I simply could not ignore.
This series was found in the Guardian Unlimited (http://sport.guardian.co.uk.html). The first article was about Seve Ballesteros who is suffering from severe osteoarthritis. In this article it reviews several other sports/sports figures that are prone to accumulated damage including track and field (Carl Lewis) and famous British jockey Willie Carson.
Of course soccer and Rugby were stand outs. Over 50% of the professional player questioned had at least one joint replaced by age 40! Many had been forced to retire and could not even undertake a coaching career because of the problems associated with their joints.
The total cost to the Professional Soccer Association was the equivalent of over $3,000,000/year!
BUT, they did something about it:" This concern is one reason why, proper to the World Cup, England recruited a sponsor in the form of a supplement manufacturer that provided them with fish oil capsules clinically proved to help protect joints."
I repeat, "Clinically proved to help joints!"
Our own football here is even worse on joints since it is very much a full contact sport. But the NFL has a certification program as I told you several weeks ago that excludes all but the richest supplement manufacturers from participating...like they need the money!!!!
If they were truly concerned about the welfare of their athletes they would search out the finest supplements and institute a universal program of supplementation with Pharmaceutical Grade Fish Oil among others!
The next article is about Paddy Doyle who is officially the World's Fittest Man. This individual has broken 124 world fitness records in his 38 years, and he clearly not done yet! In a revealing article from the same site (sport.guardain.co.uk) he reveals his training routines and supplementation.
This man would not miss his Fish Oil for the "Joints and the digestion".
The final article in this series was about an individual named "Beanpole Jones" aka Chris Jones the latest darling of the rugby seen. While naturally gifted in the sport he is a bit thin at 15 stone (ok friends from the UK help me with the translation to pounds)! As nearly as I can tell this puts him at about 210 lbs. In order to beef him up and keep the weight he gains as muscle guess what they are using. Yep Fish Oil for its fat burning qualities.
My May 10 email to you was about using my products to optimize fat loss. The Brits understand that if you combine a fat losing protein sparing supplement with proper training you get a leaner stronger athlete. More weight is converted to muscle.
And now the PROOF of the Pudding. In Part 1, June 8 we have real world testimonials by athletes as to the effectiveness of Fish Oil for performance. Below are a whole string of studies that show you why The Combination of fish Oil and Regenerizer is a must for every athlete!
The first study below is a rat study but is applicable to humans of course. It essential validates the use of fish Oil for the best muscle to fat ratios If you don't want to read the whole study read the last few lines for the "Punch".
1: Obes Res. 2002 Sep;10(9):947-55.
Effects of dietary fatty acids and exercise on body-weight regulation and
metabolism in rats.
Pellizzon M, Buison A, Ordiz F Jr, Santa Ana L, Jen KL.
Department of Nutrition and Food Science, Wayne State University, Detroit, MI
48202, USA.
OBJECTIVE: To assess the interaction of high-fat diets (HF) made with different
dietary fatty acids and exercise on body-weight regulation, adiposity, and
metabolism. RESEARCH METHODS AND PROCEDURES: Male Wistar rats born to dams fed
HF diets (40% w/w) made with either fish oil (FO), soybean oil (SO), or palm oil
(PO) were fed diets similar to their dams and divided randomly into exercise
(EX, swimming) or sedentary control (SD) groups when they were 9 weeks old. EX
lasted for 6 weeks. Twenty-four hours after the last EX bout, fasted rats were
killed by decapitation. Chemical analyses and body composition analysis were
conducted. RESULTS: The results demonstrated that different fatty acids had
different effects on body weight, composition, and metabolism. SO-fed rats
gained the most weight and fat. EX reduced body weight of FO- and PO-fed rats,
but SO-fed rats were still heavier and fatter than other rats. Data from SO- and
PO-fed rats suggested that they are insulin resistant and that EX normalized
this abnormality. Of the three HF diets used, FO produced the least adverse
effects compared with PO and SO. DISCUSSION: Not only the quantity of dietary
fat, but also the type of fat used, will produce different effects on body
weight and metabolism. EX ameliorates the suggested insulin resistance induced
in rats fed either highly saturated or n-6 polyunsaturated fatty acids.
Long-chain n-3 polyunsaturated fatty acids, as found in fish oil, are more
beneficial than n-6 polyunsaturated fatty acids when fed in high amounts to
rats. In addition fish oil type supplementation led to the best body composition in terms of fat/muscle ratio.
PMID: 12226144 [PubMed - indexed for MEDLINE]
The next study indicates that Omega 3 suplementation is both helpful and needed as these essential Fish Oils are used up by intense exercise as they absorb free radicals. Once again the last sentence contains the punch line.
1: Ukr Biokhim Zh. 1997 Jul-Aug;69(4):83-7.
[Lipid composition of blood plasma and erythrocyte membrane of volleyball
players under intensive physical load]
[Article in Russian]
Popichev MI, Tolkacheva NV, Kulakova SN, Konoshenko SV.
Tavrian Institute of Business and Law, Simferopol State University, Institute of
Nutrition, Russian Academy of Medical Science, Moscow, Russia.
As the result of prolonged training activity highly skilled volleyball players
have marked deficiency of fatty acids of w3 family both in the blood plasma as
erythrocyte membranes. These acids may be used in the lipid peroxidation
processes, that is proved by the facts of POL products content and their drawing
into oxidation reaction, which is certified by high level of ATP in
erythrocytes. Reduction of quantity of polyunsaturated fatty acids of w3 family
may be regarded as results of their insufficient arrival with food indicating the need for supplementation in atheletes.
PMID: 9583128 [PubMed - indexed for MEDLINE]
Previous studies have indicated that fish oil supplementation increases red blood cell (RBC) deformability, which may improve exercise performance. One such study is coming in a moment. But first the study below shows how fish oil supplementation can push the VAT (ventilatory anaerobic threshold to new heights. The VAT is the point at which your body switches over to non oxygen using pathways, and is the point at which you can no longer exercise for more than 60 sec or so. In English this means that Fish Oil helps you exercise longer and harder before you have to stop. Again if all of this is Greek to you just read the last line or so!
1: J Sports Med Phys Fitness. 1990 Jun;30(2):173-80.
Effect of fish oil supplementation and exercise on serum lipids and aerobic
fitness.
Brilla LR, Landerholm TE.
Exercise and Sport Science Laboratory, Western Washington University,
Bellingham.
The effects of fish oil supplementation and exercise were investigated in
healthy, previously sedentary males, ages 19-34. Thirty-two subjects were
assigned to four groups: control (C), fish (F), exercise (E), fish and exercise
(FE). The fish groups consumed 4 g.d-1 of omega-3 fatty acids. The exercise
groups performed aerobic exercise for one hour three per week. The study was
conducted for 10 weeks with pre and post values obtained for cholesterol,
triglycerides, HDL-cholesterol, LDL-cholesterol, maximal oxygen consumption
(VO2max), ventilatory anaerobic threshold (VAT), percent body fat, and dietary
composition of macronutrients and polyunsaturated to saturated fat (P:S) ratio.
No significant differences were noted between groups for any of the blood lipid
values, percent body fat or dietary variables. VO2max and VAT did exhibit
significant changes among groups. VO2max was greater for the exercise groups (E,
FE) as compared to the control group (p less than 0.05). E, but not FE, was
significantly greater than F. VAT was significantly greater in F, E, and FE as
compared to controls, however the control's VAT decreased slightly. The slight
improvement, although statistically non-significant, in VO2max and VAT by the F
group requires further study. This data indicates an improvement in aerobic
metabolism from aerobic exercise, alone or in combination with fish oil,
compared to controls.
PMID: 2402138 [PubMed - indexed for MEDLINE]
The next study show how fish Oil improves oxygen delivery to cells thus improving aerobic performance I men and women, although there is a small sex difference in its effect.
1: Eur J Appl Physiol Occup Physiol. 1991;63(5):393-8.
Fish diet and physical fitness in relation to membrane and serum lipids,
prostanoid metabolism and platelet aggregation in female students.
Agren JJ, Pekkarinen H, Litmanen H, Hanninen O.
Department of Physiology, University of Kuopio, Finland.
The effects of a 14-week fish diet and exercise programme on lipid metabolism
and platelet aggregation in healthy female students (n = 99) were studied. The
subjects were divided into four groups: a control group, a fish diet group (3.5
meals containing fish per week, 0.9 g n-3 fatty acids per day), an exercise
group (at least three training sessions per week) and a combined fish diet and
exercise group. The proportion of n-3 fatty acids increased at the expense of
n-6 fatty acids in platelets and erythrocyte ghosts in the fish diet groups.
Serum triglyceride concentrations tended to decrease in the fish diet and
exercise groups and a significant decrease was found in the combined fish diet
and exercise group (13%, P less than 0.05). No significant changes took place in
the other serum lipid and apolipoprotein concentrations. Platelet production of
thromboxane B2, plasma 6-keto-PGF1 alpha concentrations and adenosine
5'-diphosphate (ADP)-induced platelet aggregation also remained unchanged in all
groups during the study. However, an inverse correlation was found between
physical fitness (maximal oxygen uptake and maximal exercise intensity) and
serum triglycerides, total cholesterol, low density lipoprotein cholesterol and
platelet aggregation. This suggests that improved physical fitness is related to
beneficial changes in serum lipid concentrations and to a decreased aggregation
tendency of platelets. The responses of the female subjects to a fish diet were
similar when compared to earlier studies on male subjects. This suggests that
there are small sex differences in the efficiency of n-3 fatty acids in modifying
lipid metabolism.
PMID: 1773818 [PubMed - indexed for MEDLINE]
Next I'd like to move on to Regenerizer. A lot of people have asked me why it helps their athletic performance as well as there sex drive and mental focus. The next series of articles focuses on the athletic effects of Co Q 10 which is present in big dose in Regenerizer and of L Carnitene ( note again not the over hyped Acetyl L Carnitene!) also present in a big way in Regenerizer.
The next study shows improvements in both anaerobic and aerobic performance with Co Q.
1: Acta Physiol Scand. 1997 Nov;161(3):379-84.
Effects of ubiquinone-10 supplementation and high intensity training on physical
performance in humans.
Malm C, Svensson M, Ekblom B, Sjodin B.
Department of Physiology and Pharmacology, Karolinska Institute, Stockholm,
Sweden.
This study investigated the effects of oral supplementation with ubiquinone-10
(Q10) (n = 9) compared with a placebo (n = 9) on aerobic and anaerobic physical
performance over 22 days of supplementation. The supplementation period included
5 days of high intensity anaerobic training between days 11 and 14. The results
demonstrated, that on an anaerobic (10 x 10 s) cycling test, the placebo group
showed a significantly greater improvement than the Q10-group after a
supplementation and training period (P < 0.001). Further, the Q10 group had a
significantly lower increase in total work performed during the seven training
sessions (15 x 10 s) compared with the placebo group (P < 0.001). There was a
significant increase in maximal blood lactate accumulation during cycling in the
both groups, when compared with levels before the training and recovery period.
There was significant difference between the groups, either in VO2max
determined during running, or in submaximal and peak VO2, Rate of Perceived
Exertion, respiratory quotient, blood lactate concentration or heart rate
determined during submaximal and maximal cycling. Although significant (P =
0.1-0.3), there was evidence of higher submaximal VO2 (55-80% of VO2peak) during
cycling in the Q10-group compared with the placebo group after training and
recovery. It is concluded that with high intensity anaerobic training, there was
a significantly greater increase in anaerobic performance in the CoQ 10 group
compared with the placebo group.
Publication Types:
The next study done in Finnish cross country skiers show that CoQ improved all aspects of their performance and training!
Mol Aspects Med. 1997;18 Suppl:S283-90.
The effect of coenzyme Q10 on the exercise performance of cross-country skiers.
Ylikoski T, Piirainen J, Hanninen O, Penttinen J.
Vuokatti Sports Testcenter, Finland.
Coenzyme Q10 supplementation ( 90 mg/day) was studied in a
double-blind cross-over study of 25 Finnish top-level cross-country skiers. With
CoQ10 supplementation, all measured indexes of physical performance (AET, ANT
and VO2Max) improved significantly. During verum supplementation, 94% of the
athletes felt that the preparation had been beneficial in improving their
performance and recovery time vs. only 33% in the placebo periods.
Publication Types:
Clinical Trial
As promised a bit on why I chose L Carnitene for Regenerizer. This next study shows the positive effect of L Carnitene on the Respiratory Quotient. The respiratory Quotient is essential a measure of what types of fuels are being burned to produce energy (fat, protein etc). The lower the Respiratory Quotient, the MORE fat is being burned. This supports Regenerizer's use in the fat burning program of May 10th.
1: Int J Sports Med. 1989 Jun;10(3):169-74.
Decrease in respiratory quotient during exercise following L-carnitine
supplementation.
Gorostiaga EM, Maurer CA, Eclache JP.
Association Sport-Biologie, Lyone, France.
This study was undertaken to determine the effects of L-carnitine addition to
the diet during submaximal exercise in endurance-trained humans. Ten subjects
(VO2max: 62 ml.kg-1.min-1) performed a control test (C) (45 min of cycling at
66% of VO2max) followed by 60 min of recovery in a sitting position. Each
subject repeated this trial after 28 days of placebo (P) and L-carnitine (L-C)
treatment (double-blinded cross-over design). The dose of each treatment was 2
g/day. There were no differences between the C and P tests. The respiratory
quotient was lower (p less than 0.05) with treatment than with P or C during
exercise. In addition, oxygen uptake, heart rate, blood glycerol, and resting
plasma free fatty acid concentrations presented a significant trend toward
higher values in L-C than in the C or P groups. These observations suggest an
increased lipid utilization by muscle during exercise in the L-C-treated group.
This effect has further possibilities for improving performance during
submaximal exercise.
Publication Types:
This next study show how L Carnitene improves performance in trained athletes, especially the point at which they become fatiged and can no longer carry on( the VO2 max).
1: Eur J Appl Physiol Occup Physiol. 1985;54(2):131-5.
Effects of L-carnitine loading on the aerobic and anaerobic performance of
endurance athletes.
Marconi C, Sassi G, Carpinelli A, Cerretelli P.
L-Carnitine (L-C), a well known physiological carrier across the inner
mitochondrial membrane of activated long chain fatty acids and acceptor of acyl
groups from acyl-CoA, has been recently synthesised industrially. This has made
it possible to study the effects of L-C loading (4 g X d(-1) by mouth over a
period of 2 weeks) on the aerobic and anaerobic performance of 6 long distance
competitive walkers. As a result of the treatment: 1) mean total, free and
esterified serum L-C both at rest and shortly after completing a 120 min walk at
about 65% of the individual maximal aerobic power (VO2max) were significantly
increased; 2) VO2max increased 6%, from 54.5 +/- 3.7 (S.D.) to 57.8 +/- 4.7 m1O2
X kg(-1) X min(-1) (P less than 0.02); 3) blood lactate concentration (Lab) as a
consequence of short bouts repeated exercise (series of 10, 15 and 20 jumps off
both feet on a force platform) was unchanged; 4) heart rate, pulmonary
ventilation, oxygen consumption, and respiratory quotient in the same conditions
as for 1) were unchanged. It is concluded that, in trained athletes, as a
consequence of L-C loading VO2max is significantly raised, probably
as a result of an activation of substrate flow through the TCA cycle, whereas
the lipid contribution to metabolism in prolonged submaximal exercise remains
1: Eur J Appl Physiol Occup Physiol. 1990;61(5-6):486-90.
Comment in:
Eur J Appl Physiol Occup Physiol. 1991;62(6):450.
Influence of L-carnitine administration on maximal physical exercise.
Vecchiet L, Di Lisa F, Pieralisi G, Ripari P, Menabo R, Giamberardino MA,
Siliprandi N.
Istituto di Fisiopatologia Medica, Universita di Chieti, Italy.
The effects of L-carnitine administration on maximal exercise capacity were
studied in a double-blind, cross-over trial on ten moderately trained young men.
A quantity of 2 g of L-carnitine or a placebo were administered orally in random
order to these subjects 1 h before they began exercise on a cycle ergometer.
Exercise intensity was increased by 50-W increments every 3 min until they
became exhausted. After 72-h recovery, the same exercise regime was repeated but
this time the subjects, who had previously received L-carnitine, were now given
the placebo and vice versa. The results showed that at the maximal exercise
intensity, treatment with L-carnitine significantly increased both maximal
oxygen uptake, and power output. Moreover, at similar exercise intensities in
the L-carnitine trial oxygen uptake, carbon dioxide production, pulmonary
ventilation and plasma lactate were reduced. It is concluded that under these
experimental conditions pretreatment with L-carnitine favoured aerobic processes
resulting in a more efficient performance. Possible mechanisms producing this
effect are discussed.
Publication Types:
Clinical Trial
Randomized Controlled Trial
This next study shows that amino acid supplementation is worthless for the athlete.
1: Int J Sport Nutr. 1997 Dec;7(4):298-309.
Effects of a low-dose amino acid supplement on adaptations to cycling training
in untrained individuals.
Vukovich MD, Sharp RL, Kesl LD, Schaulis DL, King DS.
Human Performance Laboratory, Wichita State University, KS 67226, USA.
The purpose of this study was to determine if amino acid supplementation
influences blood and muscle lactate response to exercise and the time course of
the metabolic adaptations to training. Two groups of untrained males (n = 7
each) were given (double-blind) a daily supplement (2.9 g.day-1) containing a
mixture of leucine, isoleucine, valine, glutamine, and carnitine (EXP) or 3
g.day-1 of lactose (CON). Following 7 days of supplementation there was no
significant change in VO2peak, time to exhaustion (TTX) at 120% VO2peak, or
muscle and blood lactate in either EXP or CON. Subjects then initiated 6 weeks
of combined aerobic and anaerobic training on a Monark cycle ergometer. It was
found that amino acid supplementation had no effect on either blood or muscle
lactate accumulation during exercise, while supplementation resulted in a faster
adaptation in buffer capacity. Performance during intense exercise was not
improved with amino acid supplementation.
Publication Types:
So my Friend, you now know the logic behind combining Regenerizer and Fish Oil for Maximum Fat loss and maximum performance. If its good enough for the elite British athlete, its good enough for you!
So get smart, and GET STRONG with Dr Dave's BEST!!
Read More Here...
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